Which option best lists the key guidelines involved in GMP?

• A. Personal hygiene guidelines only
• B. Financial controls and budgeting
• C. Personal hygiene guidelines; Maintenance and infrastructure cleanliness; Good work practices during material handling.
• D. Marketing and labeling guidelines

Answer: (C)

GMP focuses on preventing contamination throughout production. Personal hygiene is essential because workers can introduce contaminants through hands, clothing, or illness, so practices like proper handwashing, clean attire, and reporting sickness are foundational. Maintenance and infrastructure cleanliness keep facilities and equipment in good, sanitary condition, reducing hiding places for microbes and preventing cross-contamination. Good work practices during material handling ensure that raw materials are received, stored, and managed in a way that protects quality and safety, with proper handling, storage conditions, and traceability. Together these areas form the core of GMP guidance for safe manufacturing. The other options miss important parts: personal hygiene alone doesn’t cover facility upkeep or material handling, and financial controls or marketing/labeling aren’t the GMP focus for preventing contamination in production.